Global Nucleic Acid Extraction Instruments & Reagents Market By Reagent Type: (Endonucleases, Endonucleases I, EDTA, lysozyme) By Instrument Type: (Spin Columns, Magnetic Beads) By Extraction Methods: (Solution-based method, Solid-phase based methods) By Application: (Paternity Tests, Forensic Study) End-user: (Diagnostic Centers, Hospitals & Clinics, Forensic Labs) by Region and Companies - Industry Segment Outlook, Market Assessment, Competition Scenario, Trends and Forecast to 2032

Nucleic Acid Extraction Instruments & Reagents Market Introduction:

The global Nucleic Acid Extraction Instruments & Reagents market is projected to reach a valuation of USD 15.8 Bn by 2032 at a CAGR of 11.4%, from USD 4.6 Bn in 2021.

Nucleic acids are frequently termed “the building blocks of life” These acids are found in the nuclei of cells and help synthesize proteins, replicate cells, store and transmit cell data, and govern the cell’s chemical processes.

Nucleic acid extraction is the primary step of any amplification (a process to produce multiple copies of a specific DNA sequence) test to detect a particular pathogen. Extraction ought to be simple, fast, and should show high sensitivity and specificity. It is favored that there be no requirements for special equipment or special knowledge and abilities. The final nucleic acid should be pure and simple to change for different amplification strategies.

Nucleic acid extraction comprises three significant processes: isolation, purification, and concentration. Commercial extraction units are ordinarily utilized in the clinical microbial science lab.

These units provide the fundamental requirements for nucleic acid extraction. Filtration of nucleic acids is a multi-step process, starting from cell lysis to collecting the last DNA or RNA item. In these processes, various stand-alone accessory reagents might be utilized to improve the yield or virtue of the final product. Among these incorporate particular cell lysis kits, buffers, and catalysts (like lysozyme), ensuring the powerful release of nucleic acid from cell compartments.

For eliminating toxins, endotoxin removal reagents can be helpful for samples susceptible to bacterial lipopolysaccharide contamination, for example, in plasmid DNA preparation. Nucleases, such as DNases and RNases, are valuable to extract undesirable lingering nucleic acids from RNA or DNA. In specific extraction systems like ethanol precipitation, the optional addition of glycogen can upgrade the development of the final pellet.

Types of Nucleic Acids:

• Deoxyribonucleic Acid (DNA)
• Ribonucleic Acid (RNA)
• Messenger RNA (mRNA)
• Transfer RNA (tRNA)
• Ribosomal RNA (rRNA)

Detailed Market Segmentation:

Market segmentation of the global nucleic acid extraction instruments & reagents market is based on Reagent Type, Instrument Type, Extraction Methods, Application, End-User, and Regions.

By Reagent Type:

• Endonucleases
• Endonucleases I
• Endonucleases III
• Endonuclease IV
• Endonucleases V
• Endonucleases VIII
• Benzonase
• EDTA
• lysozyme

By Instrument Type:

• Spin Columns
• Magnetic Beads
• Microfluidics
• Lab-on-a-Chip
• Liquid Handling Robots

By Extraction Methods:

• Solution-based methods
• Solid-phase based methods

By Application:

• Paternity Tests
• Forensic Study
• Disease Identification
• Genetic Engineering
• Other Applications

End-user:

• Diagnostic Centers
• Hospitals & Clinics
• Forensic Labs
• Pharmaceuticals
• Ambulatory Surgical Centers

By Region:

• North America
• Europe
• Asia Pacific
• South America
• Middle East & Africa

Market Dynamics:

The expansion of the nucleic acid extraction instruments and reagents market can be ascribed to the increasing prevalence of chronic and irresistible infections, the increasing number of patients suffering COVID-19, and a spike in the awareness and acknowledgment of customized medicine and companion diagnostics, as well as booming geriatric populations. The increasing necessity of biopharmaceuticals such as immunizations, proteins, antibodies, plasma, catalysts, biologics, and peptides for the therapy of malignant growths, neurological sicknesses, and persistent kidney infections. Besides, the spike in the pervasiveness of lifestyle illnesses, an increase in healthcare spending, and stronger economies are elements that are anticipated to further strengthen the global nucleic acid extraction instruments and reagents market over the projected timeline.

Certain extraction methods require automation systems for centrifugation which are expensive and need additional maintenance, moreover, incomplete homogenization can clog the membrane or potentially bring about contamination with proteins or genomic DNA. Adding to this, certain instruments such as magnetic beads, etc., possess the risk of RNA sample contamination. Such factors may hinder market growth prospects for this global industry.

Nucleic acid extraction kits are generally utilized in clinical microbial science labs. These test kits lend essential prerequisites to nucleic acid extraction. Higher usage levels and the necessity of these kits are expected to create lucrative opportunities for this market over the forecast period.

Competitive Landscape:

• Thermo Fisher Scientific Inc.
• Agilent Technologies
• Bio-Rad Laboratories Inc.
• Merck KGaA
• Danaher Corporation
• F. Hoffmann-La Roche Ltd.
• Illumina Inc.
• Takara Bio Inc.
• Promega Corporation
• QIAGEN.

Key Developments:

• In November 2020, QIAGEN entered into a strategic collaboration with BioNTech SE to develop and commercialize a tissue-based companion diagnostic. The test covers a panel of Human Papillomavirus (HPV) genotypes, paired with investigational treatment BNT113, to identify patients whose cancers are caused by Human Papillomavirus (HPV) infections.
• In September 2020, Thermo Fisher Scientific announced a collaboration of the Thermo Fisher Precision Medicine Science Center (PMSC) with the University of Nebraska Medical Center and AstraZeneca to develop novel solutions for unmet needs in clinical biomarker characterization and discovery.