Global Gene Synthesis Market By Method Type (Solid-phase Synthesis, Chip-based Synthesis, and PCR-based Enzyme Synthesis), By Service (Antibody DNA Synthesis, Viral DNA Synthesis, and Other Services), By Application (Gene & Cell Therapy Development, Vaccine Development, Disease Diagnosis, and Other Applications) By End-use (Biotechnology & Pharmaceutical Companies, Academic & Government Research Institutes, and Contract Research Organizations), By Region and Companies - Industry Segment Outlook, Market Assessment, Competition Scenario, Trends and Forecast 2022-2032
- Published date: Nov 2021
- Report ID: 14565
- Number of Pages: 304
- Format:
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Gene Synthesis Market Overview:
The global gene synthesis market value was USD 1,517 million in 2021. The market is expected to grow at a CAGR of 19.2% from 2022-2032.
The market’s key drivers are the supportive government policies for synthetic biology. With the increasing demand for synthetic biology, investors have turned their attention to this field in recent years.
Global Gene Synthesis Market Scope:
Method Analysis:
Solid-phase synthesis was the segment that earned the most revenue share, more than 37%, in 2021. This is due to the fastest adoption rate of the technology over the last few years.
Its high accuracy and widespread adoption in therapy development and research settings further encourage this method to be used. However, it is expensive and produces low results, making it difficult to be used in certain situations.
There are other options. Over the forecast period, significant CAGRs are expected for both chip-based and PCR-based methods. These methods can produce larger fragments at a slower rate, which allows for their increased usage. PCR-based gene sequencing is also possible using cell systems.
The relative ease of artificial gene synthetization made possible by different methods has allowed potential scientific innovators to significantly speed up the preparation of DNA fragments needed for the R&D and development of synthetic nucleic-based therapeutics.
This is expected to increase the adoption across all three techniques based on research needs.
Service Analysis:
The segment of antibody DNA synthesizing dominated the market, accounting for more than 61.3% of its revenue in 2021. This segment is well-represented by many market players who offer services for antibody synthesis.
Services are being offered by companies to pharma/biotech and research institutes to allow the cloning/synthesis of antibody heavy/light chains into any custom vector. A growing number of virus vector-related R&D activities will result in the viral gene synthesis section registering the highest CAGR from 2023 to 2032.
Companies also participate in the synthesis of fragments for all structural and non-structural protein genes. This has enabled the acquisition of virus recombinant genes and stimulated research on protein structural biology.
The virus-related target genome synthesis was mass-produced and is for research only. These factors are expected to help to grow this segment.
Application Analysis:
The market can be further divided by end-use into IT and telecom, BFSI and healthcare, as well as IT and telecom and manufacturing. In 2021, the market share for BFSI was around 20%.
BFSI industry incumbents use application servers to create banking applications that can support multiple user sessions simultaneously. The healthcare vertical is utilizing mobile applications aggressively to provide medical assistance to patients at remote locations in real-time, driving growth.
The other segment includes various end-use segments such as defense, education, and media and entertainment. This segment is expected to grow due to the increasing preference for and increased adoption of application servers in organizations working in other industries and verticals.
Market growth will be driven by the increasing adoption of connected devices, Internet of Things devices (IoT), and connected sensors by incumbents from different industries and verticals.
The growth is also supported by key applications such as real-time data analytics for businesses, personal communication apps, and work collaboration apps.
End-Use Analysis:
The global market’s top segment was the academic and government research institution, with over 54% of revenue. Because of the high use of gene synthesis services in research environments, this segment is predicted to grow faster at a CAGR of more than 54% between 2023-2032.
Research institutes collaborate with service providers to speed up their research programs that involve the synthesis of and characterization of gene fragments.
The segment biotechnology & pharmaceutical businesses are expected to grow significantly over the forecast period. The segment growth is expected to be aided by the increasing use of synthesis biology in biotech companies to develop new disease management strategies.
Key Market Players:
By Method:
- Solid-phase Synthesis
- Chip-based Synthesis
- PCR-based Enzyme Synthesis
By Service:
- Antibody DNA Synthesis
- Viral DNA Synthesis
- Other Services
By Application:
- Gene & Cell Therapy Development
- Vaccine Development
- Disease Diagnosis
- Other Applications
By End-use:
- Biotechnology & Pharmaceutical Companies
- Academic & Government Research Institutes
- Contract Research Organizations
Market Dynamics:
The market has experienced new growth opportunities due to the COVID-19 outbreak. Scientists are exploring new avenues in this space that can lead to revenue growth.
To aid in the development of more accurate and reliable diagnostic tests, scientists at the National Institute of Standards and Technology(NIST) have synthesized gene fragments for the COVID-19 viral virus. Around USD 8 Billion was invested by private and public financing in the field of synthetic biology in 2021.
The advancements in synthetic DNA technology are becoming more popular as a way to address growing concerns regarding emerging pathogens as well as the threat of the next global epidemic.
This promising strategy for quickly propagating and helping to characterize genes can quickly progress to address the current SARS/CoV-2 pandemic, as well as any future pandemics involving new pathogens.
Targeted therapy has gained increasing attention over the years from both biotechnology and pharmaceutical companies. It is a vital method of disease control.
Targeted therapy combined with chemotherapy or immunotherapy will experience significant growth in the near future. This will open up lucrative opportunities for emerging and key players in this market.
The shortage of skilled professionals working in the field of gene synthesis or biotechnology is a major obstacle to the market’s growth.
This is because market players require highly trained and experienced staff at their facilities. In order to help the market, grow, companies are now collaborating and offering online workshops, on-site training, and sponsored projects.
Regional Analysis:
North America was the dominant market for application servers in 2021, accounting for over 40% of all revenue. North America is well-known for its early adoption of new technologies and high penetration of mobile communication devices.
Canada and the United States are mature markets when it comes to the early adoption of new and emerging technologies. Businesses based in North America have a high adoption rate for application servers. Many market leaders are also found in North America.
The Asia Pacific will be the fastest-growing regional market. The Asia Pacific is well-known for its multifold growth in e-commerce, manufacturing, and the widespread use of smartphones. It also has the rollout of high-speed wireless internet networks and the proliferation of smartphones.
Other key factors expected to drive the region’s growth include the growing number of IT service providers and startups that offer service-based solutions, as well as the increased adoption of new technologies, especially in India and China.
Кеу Regions and Countries covered іn thе rероrt:
- North America
- US
- Canada
- Mexico
- Europe
- Germany
- UK
- France
- Italy
- Russia
- Spain
- Rest of Europe
- APAC
- China
- Japan
- South Korea
- India
- Rest of Asia-Pacific
- South America
- Brazil
- Argentina
- Rest of South America
- MEA
- GCC
- South Africa
- Israel
- Rest of MEA
Key Companies & Market share Analysis:
In the future, the market is likely to see increased competition. The market is experiencing increasing competition due to the influx of new market players. These players are actively involved in strategizing in order to capitalize on the untapped areas and increase their market presence by offering a broad range of services.
Some of the leading players in the global gene-synthesis market are.
Key Market Players:
- GenScript
- Brooks Automation, Inc. (GENEWIZ)
- Boster Biotechnology
- Twist Bioscience
- ProteoGenix
- Biomatik
- ProMab Biotechnologies, Inc.
- Thermo Fisher Scientific, Inc.
- Integrated DNA Technologies, Inc.
- OriGene Technologies, Inc.
- Other Key Players
For the Gene Synthesis Market research study, the following years have been considered to estimate the market size:
Attribute Report Details Historical Years
2016-2020
Base Year
2021
Estimated Year
2022
Short Term Projection Year
2028
Projected Year
2023
Long Term Projection Year
2032
Report Coverage
Competitive Landscape, Revenue analysis, Company Share Analysis, Manufacturers Analysis, Volume by Manufacturers, Key Segments, Key company analysis, Market Trends, Distribution Channel, Market Dynamics, COVID-19 Impact Analysis, strategy for existing players to grab maximum market share, and more.
Regional Scope
North America, Europe, Asia-Pacific, South America, Middle East & Africa
Country Scope
United States, Canada and Mexico, Germany, France, UK, Russia and Italy, China, Japan, Korea, India and Southeast Asia, Brazil, Argentina, Colombia etc.Saudi Arabia, UAE, Egypt, Nigeria and South Africa
Frequently Asked Questions (FAQ)
Q: What is the gene synthesis market size in year 2021?The gene synthesis market size was US$1,517 million in 2021.
Q: What is the CAGR for the gene synthesis market?The gene synthesis market is expected to grow at a CAGR of 19.2% during 2023-2032.
Q: What are the segments covered in the gene synthesis market report?Market.US has segmented the gene synthesis market by geography (North America, Europe, APAC, South America, and the Middle East and Africa). By method, the market has been segmented into Solid-phase Synthesis, Chip-based Synthesis, PCR-based Enzyme Synthesis. By service, the market has been segmented into Antibody DNA Synthesis, Viral DNA Synthesis, Others. By Application, the market has been segmented into Gene & Cell Therapy Development, Vaccine Development, Disease Diagnosis, Others. By End-Use, the market has been further divided into it Biotechnology & Pharmaceutical Companies, Academic & Government Research Institutes, Contract Research Organizations.
Q: Who are the key players in the gene synthesis market?GenScript, Brooks Automation, Inc. (GENEWIZ), Boster Biotechnology, Twist Bioscience, ProteoGenix, Biomatik, ProMab Biotechnologies, Inc., Thermo Fisher Scientific, Inc., Integrated DNA Technologies, Inc., OriGene Technologies, Inc., are the key vendors in the gene synthesis market
Q: Which region is more attractive for vendors in the gene synthesis market?North America is the region having high revenue share 40% among the others. Therefore, North America gene synthesis market is expected to garner significant business opportunities for the vendors during the forecast period.
Q: What are the key markets for gene synthesis ?Key markets for gene synthesis are the US, Canada, Mexico, France, Germany, etc.
Q: Which segment has the largest share in the gene synthesis market?In the gene synthesis market, vendors should focus on grabbing business opportunities from the solid-phase synthesis segment as it accounted for the largest market share in the base year.
- GenScript
- Brooks Automation, Inc. (GENEWIZ)
- Boster Biotechnology
- Twist Bioscience
- ProteoGenix
- Biomatik
- ProMab Biotechnologies, Inc.
- Thermo Fisher Scientific, Inc.
- Integrated DNA Technologies, Inc.
- OriGene Technologies, Inc.
- Other Key Players
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